海角黑料

School of Pharmacy

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Chee Mun Fang

Honorary Associate Professor,

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Biography

I obtained my Ph.D. in the filed of immunology and vaccinology from University of Malaya, Malaysia in 2006. After completing my Ph.D. I joined the Salmonella Live Vector Vaccine Unit at the Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, USA focusing on the development of attenuated bacterial live vector, Salmonella, as a carrier for vaccine delivery. Subsequently, I moved to another lab in Biology Department, John Hopkins University, Baltimore USA as a senior postdoctoral research fellow and worked on understanding the role of Interferon Regulatory Factors 5 (IRF5) in development and effector functions of B cells. Prior to join the 海角黑料 Malaysia Campus in 2014, I worked as lecturer for several years in local institutions mainly involved in teaching Immunology and Microbiology modules for medical, pharmacy and life sciences students.

Teaching Summary

Module convener: Therapeutic Immunology (LIFE4131); Medical Microbiology and Parasitology (LIFE2102); Biomedical Science Industrial Training (LIFE2101)

Involved in the teaching of : Human Physiology (LIFE1052), Medical Microbiology and Parasitology (LIFE2102); Asthma, Allergy and Immune disease (PHAR2017); Renal and Endocrine Diseases (PHAR2019); Core Skills in Biomedical Sciences (LIFE1054); Human Disease (LIFE1055); Therapeutic Immunology (LIFE4131)

Supervision: Final Year Projects, Postgraduate research studies

Research Summary

My research primarily focuses on understanding the role of Interferon and Interferon Regulatory Factors (IRFs) in development of lymphoid cells, allergy, autoimmune diseases and carcinogenesis. My… read more

Recent Publications

  • YAP, ZHI H, KONG, WEI YANG, AZEEZ, ABDUR RAHMAAN, FANG, CHEE-MUN and NGAI, SIEW CHING, 2022. Anti-Cancer Effects of Epigenetics Drugs Scriptaid and Zebularine in Human Breast Adenocarcinoma Cells Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). 22(8), 1582-1591
  • LOH, FEI-KEAN, NATHAN, SHEILA, CHOW, SEK-CHUEN and FANG, CHEE-MUN, 2022. Cytolysin A-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant Salmonella Typhi vaccine strain Letters in Applied Microbiology.
  • SONIA HOW MING WONG, CHEE-MUN FANG, HWEI-SAN LOH and SIEW CHING NGAI, 2021. Journal of Molecular Biology and Biotechnology. 29(1), 26-41
  • LOH, FEI-KEAN, NATHAN, SHEILA, CHOW, SEK-CHUEN and FANG, CHEE-MUN, 2021. Immunogenicity and protection efficacy of enhanced fitness recombinant Salmonella Typhi monovalent and bivalent vaccine strains against acute toxoplasmosis Pathogens and global health. 115(6), 392-404

Current Research

My research primarily focuses on understanding the role of Interferon and Interferon Regulatory Factors (IRFs) in development of lymphoid cells, allergy, autoimmune diseases and carcinogenesis. My current works include vaccine development against various infectious diseases by using Salmonella as a carrier for vaccine delivery as well as characterization of immunomodulatory properties of bioactive fraction from plant materials.

  • YAP, ZHI H, KONG, WEI YANG, AZEEZ, ABDUR RAHMAAN, FANG, CHEE-MUN and NGAI, SIEW CHING, 2022. Anti-Cancer Effects of Epigenetics Drugs Scriptaid and Zebularine in Human Breast Adenocarcinoma Cells Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents). 22(8), 1582-1591
  • LOH, FEI-KEAN, NATHAN, SHEILA, CHOW, SEK-CHUEN and FANG, CHEE-MUN, 2022. Cytolysin A-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant Salmonella Typhi vaccine strain Letters in Applied Microbiology.
  • SONIA HOW MING WONG, CHEE-MUN FANG, HWEI-SAN LOH and SIEW CHING NGAI, 2021. Journal of Molecular Biology and Biotechnology. 29(1), 26-41
  • LOH, FEI-KEAN, NATHAN, SHEILA, CHOW, SEK-CHUEN and FANG, CHEE-MUN, 2021. Immunogenicity and protection efficacy of enhanced fitness recombinant Salmonella Typhi monovalent and bivalent vaccine strains against acute toxoplasmosis Pathogens and global health. 115(6), 392-404
  • CHONG, CE LYNN, FANG, CHEE MUN, PUNG, SWEE YONG, ONG, CHIN ENG, PUNG, YUH FEN, KONG, CIN and PAN, YAN, 2021. Current updates on the in vivo assessment of zinc oxide nanoparticles toxicity using animal models BioNanoScience. 11(2), 590-620
  • HUI, MARTHA LOK-YUNG, TAN, LOH TENG-HERN, LETCHUMANAN, VENGADESH, HE, YA-WEN, FANG, CHEE-MUN, CHAN, KOK-GAN, LAW, JODI WOAN-FEI and LEE, LEARN-HAN, 2021. The extremophilic Actinobacteria: From microbes to medicine Antibiotics. 10(6), 682
  • CHONG, ZHI XIONG, YEAP, SWEE KEONG, HO, WAN YONG and FANG, CHEE MUN, 2021. Unveiling the tumour-regulatory roles of miR-1275 in cancer Pathology-Research and Practice. 153745
  • MAHENDRAN, ARUN SURIA KARNAN, LIM, YIN SZE, FANG, CHEE-MUN, LOH, HWEI-SAN and LE, CHENG FOH, 2020. FRONTIERS IN PHARMACOLOGY. 11, 1475
  • ILORI, NAOMI TEMITOPE OLUBUSOLA, LIEW, CRYSTAL XIAO-QI and FANG, CHEE-MUN, 2020. Molecular Biology Reports. 1-12
  • KAUR, ASHWINDER and FANG, CHEE-MUN, 2020. Generation of stably expressing IRF5 spliced isoform in Jurkat cells: Progress In Microbes & Molecular Biology Progress In Microbes & Molecular Biology. 3(1),
  • KAUR, ASHWINDER and FANG, CHEE-MUN, 2020. An overview of the human immune system and the role of interferon regulatory factors (IRFs): Progress In Microbes & Molecular Biology Progress In Microbes & Molecular Biology. 3(1),
  • MAHENDRAN, ARUN SURIA KARNAN, LIM, YIN SZE, FANG, CHEE-MUN, LOH, HWEI-SAN and LE, CHENG FOH, 2020. Frontiers in Pharmacology. 11, 1475
  • KONG, WEI YANG, YEE, ZONG YANG, MAI, CHUN WAI, FANG, CHEE-MUN, ABDULLAH, SYAHRIL and NGAI, SIEW CHING, 2019. Heliyon. 5(9), e02468
  • LOH, FEI-KEAN, NATHAN, SHEILA, CHOW, SEK-CHUEN and FANG, CHEE-MUN, 2019. Vaccine. 37(30), 3989-4000
  • PANG, EE LEEN, PEYRET, HADRIEN, RAMIREZ, ALEX, LOH, HWEI-SAN, LAI, KOK-SONG, FANG, CHEE-MUN, ROSENBERG, WILLIAM M and LOMONOSSOFF, GEORGE P, 2019. Frontiers in plant science. 10, 455
  • WONG, SONIA HOW MING, KONG, WEI YANG, FANG, CHEE-MUN, LOH, HWEI-SAN, CHUAH, LAY-HONG, ABDULLAH, SYAHRIL and NGAI, SIEW CHING, 2019. Critical reviews in oncology/hematology. 143, 81-94
  • SONIA HOW MING WONG, CHEE MUN FANG, LAY-HONG CHUAH, CHEE ONN LEONG and SIEW CHING NGAI, 2018. Critical Reviews in Oncology/Hematology. 121, 11-22.
  • KAUR A, LEE LH, CHOW SC and FANG CM, 2018. International reviews of immunology. 37(5), 229-248
  • LE CF, KAILAIVASAN TH, CHOW SC, ABDULLAH Z, LING SK and FANG CM, 2017. International immunopharmacology. 44, 203-210
  • LE, CHENG-FOH, KAILAIVASAN, THINA HAREESH, CHOW, SEK-CHUEN, ABDULLAH, ZUNOLIZA, LING, SUI-KIONG and FANG, CHEE-MUN, 2017. INTERNATIONAL IMMUNOPHARMACOLOGY. 44, 203-210
  • LE, CHENG-FOH, FANG, CHEE-MUN and SEKARAN, SHAMALA DEVI, 2017. Antimicrobial agents and chemotherapy. 61(4),
  • AZMAN AS, OTHMAN I, FANG CM, CHAN KG, GOH BH and LEE LH, 2017. Indian journal of microbiology. 57(2), 177-187
  • LE, CHENG-FOH, FANG, CHEE-MUN and SEKARAN, SHAMALA DEVI, 2017. Antimicrobial agents and chemotherapy. 61(4),
  • ADZZIE-SHAZLEEN AZMAN, IEKHSAN OTHMAN, CHEE-MUN FANG, KOK-GAN CHAN, BEY-HING GOH and LEARN-HAN LEE, 2016. Indian Journal of Microbiology. 1鈥�11 (In Press.)
  • LEE L, AZMAN A, ZAINAL N, ENG S, FANG C, HONG K and CHAN K, 2014. International journal of systematic and evolutionary microbiology. 64(Pt 4), 1194-201
  • CAO H, DAI P, WANG W, LI H, YUAN J, WANG F, FANG C, PITHA PM, LIU J, CONDIT RC, MCFADDEN G, MERGHOUB T, HOUGHTON AN, YOUNG JW, SHUMAN S and DENG L, 2012. PloS one. 7(5), e36823
  • PANCHANATHAN R, LIU H, LIU H, FANG C, ERICKSON LD, PITHA PM and CHOUBEY D, 2012. Journal of immunology (Baltimore, Md. : 1950). 188(1), 270-8
  • YAIW, KOON CHU, EU, LIN CHUAN, FANG, CHEE MUN, ONG, BENG BENG, QVIST, RAJES and WONG, KUM THONG, 2012. No apparent association between beta-amyloid deposition and apolipoprotein E genotype in the non-demented aging brain in a Malaysian population NEUROLOGY ASIA. 17(4), 325-330
  • FANG, C-M, ROY, S., NIELSEN, E., PAUL, M., MAUL, R., PAUN, A., KOENTGEN, F., RAVAL, F. M., SZOMOLANYI-TSUDA, E. and PITHA, P. M., 2012. GENES AND IMMUNITY. 13(5), 421-430
  • DAI P, CAO H, MERGHOUB T, AVOGADRI F, WANG W, PARIKH T, FANG C, PITHA PM, FITZGERALD KA, RAHMAN MM, MCFADDEN G, HU X, HOUGHTON AN, SHUMAN S and DENG L, 2011. Journal of virology. 85(20), 10814-25
  • LIEN C, FANG C, HUSO D, LIVAK F, LU R and PITHA PM, 2010. Proceedings of the National Academy of Sciences of the United States of America. 107(10), 4664-8
  • FANG, CHEE-MUN, LEE, HUBERT, STAGER, SIMONA and PITHA, PAULA M., 2010. CYTOKINE. 52(1-2), 61-61
  • DAI, P., CAO, H., WANG, F., MERGHOUB, T., FANG, C., PITHA-ROWE, P., WAGGONER, L., FITZGERALD, K. A., RICE, A., MOYER, R., HOUGHTON, A., SHUMAN, S. and DENG, L., 2010. Heat-treated vaccinia virus induces type I IFN production in dendritic cells and macrophages through distinct pathways JOURNAL OF INVESTIGATIVE DERMATOLOGY. 130, S122-S122
  • FANG C, WANG JY, CHINCHILLA M, LEVINE MM, BLACKWELDER WC and GALEN JE, 2008. Infection and immunity. 76(10), 4422-30
  • FANG, C. -M., WANG, J., CHINCHILLA, M., LEVINE, M. M. and GALEN, J. E., 2008. Development of Antimicrobial Peptide Microcin H47 as an Alternate System for Plasmid Selection in Attenuated Bacterial Live Vectors Abstracts of the General Meeting of the American Society for Microbiology. 108, 251
  • FANG, C. M., Z. F. ZAINUDDIN, M. MUSA, M. N. NORAZMI and K. L. THONG, 2007. Evaluation of the delivery modes and their effects on the antigenicity properties of a synthetic multivalent mycobacterial gene in mice AsPac J. Mol. Biol. Biotechnol. 15(2), 69-79
  • FANG C, ZAINUDDIN ZF, MUSA M and THONG K, 2006. Protein expression and purification. 47(2), 341-7
  • CHEE-MUN FANG and JAMES E GALEN, Microcin h47 plasmid selection system 8728760 04/03/2008 00:00:00

School of Pharmacy

海角黑料
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