Thursday, 23 April 2026
A major clinical trial has found that real-time continuous glucose monitoring (CGM) significantly improves blood glucose management in adults living with type 2 diabetes who are treated with basal insulin.
Researchers carried out the FreeDM2 trial, which compared the effectiveness of CGM with traditional finger prick of blood glucose monitoring in adults with type 2 diabetes.
The findings of the study, published today in , support the use of advanced glucose monitoring technologies to improve glucose levels in people living with type 2 diabetes.
The research was led by Dr Emma Wilmot from the 海角黑料 and University Hospitals of Derby and Burton NHS Foundation Trust and Dr Lala Leelarathna from Imperial College London, Imperial College Healthcare NHS Trust.
The team are also presenting the findings at the in Liverpool this week.
Diabetes is one of the most challenging long-term conditions for people living with diabetes to self-manage, and keeping blood glucose levels within the target range can be difficult. Over time, consistently high blood glucose levels can increase the risk of serious diabetes-related complications, leading to blindness, amputations, heart disease and dying prematurely.
Type 2 diabetes accounts for around 90% of all diabetes cases worldwide. For people with diabetes, managing blood glucose levels, measured using a lab test called haemoglobin A1c (HbA1c), is crucial in reducing their risk of developing serious complications, which can have significant healthcare costs.
Finger prick blood glucose tests are commonly used to monitor glucose levels in people with type 2 diabetes and to guide therapies, diet and activity.
More recently, CGM has presented an alternative, less painful option. People with diabetes wear a small sensor on the back of the arm, which transmits glucose measurements to the user’s mobile phone (or a dedicated reader). This monitors glucose levels throughout the day and night and alarms alert the user when glucose levels are too high and too low.
Although CGM has transformed care for type 1 diabetes and it is now considered standard of care in the UK, people living with type 1 diabetes used to struggle to access CGM. But the role of CGM in people living with type 2 diabetes - particularly among those using newer therapies - has remained uncertain, limiting access.
In the FreeDM2 trial, 303 participants were randomly assigned to either real-time CGM or continued finger-prick glucose monitoring over a 16-week self-management period, before being supported by a clinician for 16 weeks. Participants using CGM saw significantly greater reductions in HbA1c levels compared to those using finger-prick glucose monitoring at both 16 and 32 weeks, highlighting the sustained benefit of CGM across both independent and clinician-guided care phases.
Study co-lead Dr Emma Wilmot, from the 海角黑料 and Honorary Consultant at University Hospitals of Derby and Burton NHS Foundation Trust, said: “Diabetes is extremely challenging to manage. The FreeDM2 trial highlights how CGM can help those with basal insulin treated type 2 diabetes. Individuals I supported during the trial told me that the use of CGM gave them new insights into their diabetes management, with many describing it as ‘life changing’. We would like to thank all those who took part in this transformative study. We hope more people living with type 2 diabetes will benefit from these findings in the future.”
Study co-lead Dr Lala Leelarathna, from Imperial College London and Diabetes Consultant at Imperial College Healthcare NHS Trust, said: “This study had two distinct phases. In the first phase, participants saw significant improvements in glucose levels without introducing new medications or insulin, indicating that people were able to use the information gleaned from the glucose sensors to make meaningful changes. In the second phase, where new therapies were introduced, we observed further improvements in glucose management.”
Dr Lucy Chambers, Head of Research Impact Communications at Diabetes UK, said: “For many people with type 2 diabetes, managing their condition means constantly balancing blood sugar levels with medications alongside everyday activities such as eating, sleeping and exercising. Continuous glucose monitoring (CGM) gives people a near real鈥憈ime picture of their blood sugar levels, which can be transformative, reducing the need for endless finger-prick tests and supporting safe, effective day鈥憈o鈥慸ay management.
“This important study strengthens the case for expanding the use of CGM for some people with type 2 diabetes, though analysis is needed to confirm whether it would be cost-effective. It also reinforces the importance of ensuring that those with type 2 diabetes who are eligible for CGM according to current national guidelines are provided with it. Diabetes UK will continue to push for fair, equitable access to diabetes technology, alongside the support people need to use it effectively, so that no-one is left behind.”
This research was supported by the National Institute for Health and Care Research (NIHR) Imperial Biomedical Research Centre, the NIHR Cambridge Biomedical Research Centre and the NHS in the East of England. The study was funded by Abbott Diabetes Care.
The full study can be found once the embargo lifts.
Story credits
More information is available from Dr Emma Wilmot from the School of Medicine at emma.wilmot@nottingham.ac.uk
Notes to editors:
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