海角黑料

School of Chemistry
 

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Luisa Ciano

Assistant Professor, Faculty of Science

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Biography

Luisa is an Assistant Professor in the School of Chemistry. She grew up in Calitri, a lovely small town in the South of Italy, and obtained her Master's degree in Pharmaceutical Chemistry and Technology (summa cum laude) from the University of Naples "Federico II" in 2009. She then moved to the UK to start her doctoral studies at the University of York on potential anti-cancer compounds under the supervision of Prof Paul Walton and Dr Jason Lynam, receiving her PhD in Chemistry in 2013. Luisa remained in York for a PDRA position in organometallic-chemistry with Dr Jason Lynam, followed by a PDRA position with Profs Paul Walton and Gideon Davies FRS to investigate the mechanism of action of lytic polysaccharide monooxygenases (LPMOs), developing her interest in metallo-enzymes and Electron Paramagnetic Resonance (EPR) Spectroscopy. In 2019, she moved to the University of Manchester as a PDRA for the EPSRC National EPR Facility and Service, working with Profs David Collison and Eric McInnes. Luisa joined the 海角黑料 as a Anne McLaren Research Fellow in October 2019 to work on polysaccharide degrading enzymes. She has been an Assistant Professor in the School of Chemistry since 2022.

Teaching Summary

I am the module convenor and a contributor for the Y3 Module "Protein Structure and Function, Biospectroscopy and Bioinformatics". I am also an academic tutor for several Inorganic modules, and the… read more

Research Summary

The group's research interest focuses in understanding the interaction between polysaccharide-active enzymes and their natural substrates for applications in the fields of biofuel production and… read more

Selected Publications

  • CIANO, LUISA, PARADISI, ALESSANDRO, HEMSWORTH, GLYN R, TOVBORG, MORTEN, DAVIES, GIDEON J and WALTON, PAUL H, 2020. Dalton transactions (Cambridge, England : 2003). 49(11), 3413-3422
  • COURTADE, GASTON, CIANO, LUISA, PARADISI, ALESSANDRO, LINDLEY, PETER J., FORSBERG, ZARAH, SORLIE, MORTEN, WIMMER, REINHARD, DAVIES, GIDEON J., EIJSINK, VINCENT G. H., WALTON, PAUL H. and AACHMANN, FINN L., 2020. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(32), 19178-19189
  • FRANDSEN, KRISTIAN E. H., SIMMONS, THOMAS J., DUPREE, PAUL, POULSEN, JENS-CHRISTIAN N., HEMSWORTH, GLYN R., CIANO, LUISA, JOHNSTON, ESTHER M., TOVBORG, MORTEN, JOHANSEN, KATJA S., VON FREIESLEBEN, PERNILLE, MARMUSE, LAURENCE, FORT, SEBASTIEN, COTTAZ, SYLVAIN, DRIGUEZ, HUGUES, HENRISSAT, BERNARD, LENFANT, NICOLAS, TUNA, FLORIANA, BALDANSUREN, AMGALANBAATAR, DAVIES, GIDEON J., LO LEGGIO, LEILA and WALTON, PAUL H., 2016. NATURE CHEMICAL BIOLOGY. 12(4), 298-+
  • SABBADIN, FEDERICO, HEMSWORTH, GLYN R., CIANO, LUISA, HENRISSAT, BERNARD, DUPREE, PAUL, TRYFONA, THEODORA, MARQUES, RITA D. S., SWEENEY, SEAN T., BESSER, KATRIN, ELIAS, LUISA, PESANTE, GIOVANNA, LI, YI, DOWLE, ADAM A., BATES, RACHEL, GOMEZ, LEONARDO D., SIMISTER, RACHAEL, DAVIES, GIDEON J., WALTON, PAUL H., BRUCE, NEIL C. and MCQUEEN-MASON, SIMON J., 2018. NATURE COMMUNICATIONS. 9,

I am the Director for Equality, Diversity and Inclusion for the School of Chemistry since Oct 2022. I have also been a committee member for the RSC Inorganic Biochemistry Discussion Group (IBDG) since 2021.

I am the module convenor and a contributor for the Y3 Module "Protein Structure and Function, Biospectroscopy and Bioinformatics". I am also an academic tutor for several Inorganic modules, and the Y1 and Y2 Inorganic teaching labs.

Current Research

The group's research interest focuses in understanding the interaction between polysaccharide-active enzymes and their natural substrates for applications in the fields of biofuel production and sustainable chemistry. Other lines of research involve the discovery and characterisation of organisms and enzymes for plastic valorisation, and the design and characterisation LPMO-mimics.

Past Research

Past research focussed on anti-cancer compounds (PhD), Ru and Au organometallic chemistry (PDRA) and Cu-metalloenzymes, in particular lytic polysaccharide monooxygenases (PDRA).

  • FRANCO CAIRO, JOAO PAULO L., MANDELLI, FERNANDA, TRAMONTINA, ROBSON, CANNELLA, DAVID, PARADISI, ALESSANDRO, CIANO, LUISA, FERREIRA, MARCEL R., LIBERATO, MARCELO, V, BRENELLI, LIVIA B., GONCALVES, THIAGO A., RODRIGUES, GISELE N., ALVAREZ, THABATA M., MOFATTO, LUCIANA S., CARAZZOLLE, MARCELO F., PRADELLA, JOSE G. C., LEME, ADRIANA F. PAES, COSTA-LEONARDO, ANA M., OLIVEIRA-NETO, MARIO, DAMASIO, ANDRE, DAVIES, GIDEON J., FELBY, CLAUS, WALTON, PAUL H. and SQUINA, FABIO M., 2022. Oxidative cleavage of polysaccharides by a termite-derived superoxide dismutase boosts the degradation of biomass by glycoside hydrolases GREEN CHEMISTRY. 24(12), 4845-4858
  • SERRA, ILENIA, PICCININI, DANIELE, PARADISI, ALESSANDRO, CIANO, LUISA, BELLEI, MARZIA, BORTOLOTTI, CARLO AUGUSTO, BATTISTUZZI, GIANANTONIO, SOLA, MARCO, WALTON, PAUL H. and DI ROCCO, GIULIA, 2021. PROTEIN SCIENCE.
  • CIANO, LUISA, PARADISI, ALESSANDRO, HEMSWORTH, GLYN R, TOVBORG, MORTEN, DAVIES, GIDEON J and WALTON, PAUL H, 2020. Dalton transactions (Cambridge, England : 2003). 49(11), 3413-3422
  • MATHIEU, YANN, OFFEN, WENDY A., FORGET, STEPHANIE M., CIANO, LUISA, VIBORG, ALEXANDER HOLM, BLAGOVA, ELENA, HENRISSAT, BERNARD, WALTON, PAUL H., DAVIES, GIDEON J. and BRUMER, HARRY, 2020. ACS CATALYSIS. 10(5), 3042-3058
  • LABOUREL, AURORE, FRANDSEN, KRISTIAN E. H., ZHANG, FENG, BROUILLY, NICOLAS, GRISEL, SACHA, HAON, MIREILLE, CIANO, LUISA, ROPARTZ, DAVID, FANUEL, MATHIEU, MARTIN, FRANCIS, NAVARRO, DAVID, ROSSO, MARIE-NOELLE, TANDRUP, TOBIAS, BISSARO, BASTIEN, JOHANSEN, KATJA S., ZERVA, ANASTASIA, WALTON, PAUL H., HENRISSAT, BERNARD, LO LEGGIO, LEILA and BERRIN, JEAN-GUY, 2020. NATURE CHEMICAL BIOLOGY. 16(3), 345-+
  • COURTADE, GASTON, CIANO, LUISA, PARADISI, ALESSANDRO, LINDLEY, PETER J., FORSBERG, ZARAH, SORLIE, MORTEN, WIMMER, REINHARD, DAVIES, GIDEON J., EIJSINK, VINCENT G. H., WALTON, PAUL H. and AACHMANN, FINN L., 2020. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117(32), 19178-19189
  • FOWLER, CLAIRE. A., SABBADIN, FEDERICO, CIANO, LUISA, HEMSWORTH, GLYN R., ELIAS, LUISA, BRUCE, NEIL, MCQUEEN-MASON, SIMON, DAVIES, GIDEON J. and WALTON, PAUL H., 2019. BIOTECHNOLOGY FOR BIOFUELS. 12(1),
  • PARADISI, ALESSANDRO, JOHNSTON, ESTHER M., TOVBORG, MORTEN, NICOLL, CALLUM R., CIANO, LUISA, DOWLE, ADAM, MCMASTER, JONATHAN, HANCOCK, Y., DAVIES, GIDEON J. and WALTON, PAUL H., 2019. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 141(46), 18585-18599
  • SABBADIN, FEDERICO, HEMSWORTH, GLYN R., CIANO, LUISA, HENRISSAT, BERNARD, DUPREE, PAUL, TRYFONA, THEODORA, MARQUES, RITA D. S., SWEENEY, SEAN T., BESSER, KATRIN, ELIAS, LUISA, PESANTE, GIOVANNA, LI, YI, DOWLE, ADAM A., BATES, RACHEL, GOMEZ, LEONARDO D., SIMISTER, RACHAEL, DAVIES, GIDEON J., WALTON, PAUL H., BRUCE, NEIL C. and MCQUEEN-MASON, SIMON J., 2018. NATURE COMMUNICATIONS. 9,
  • CIANO, LUISA, DAVIES, GIDEON J., TOLMAN, WILLIAM B. and WALTON, PAUL H., 2018. NATURE CATALYSIS. 1(8), 571-577
  • HEMSWORTH, GLYN R., CIANO, LUISA, DAVIES, GIDEON J. and WALTON, PAUL H., 2018. ENZYMES OF ENERGY TECHNOLOGY. 613, 63-90
  • COUTURIER, MARIE, LADEV脠ZE, SIMON, SULZENBACHER, GERLIND, CIANO, LUISA, FANUEL, MATHIEU, MOREAU, C脡LINE, VILLARES, ANA, CATHALA, BERNARD, CHASPOUL, FLORENCE, FRANDSEN, KRISTIAN E., LABOUREL, AURORE, HERPO脣L-GIMBERT, ISABELLE, GRISEL, SACHA, HAON, MIREILLE, LENFANT, NICOLAS, ROGNIAUX, H脡L脠NE, ROPARTZ, DAVID, DAVIES, GIDEON J., ROSSO, MARIE-NO脣LLE, WALTON, PAUL H., HENRISSAT, BERNARD and BERRIN, JEAN-GUY, 2018. Nature Chemical Biology. 14, 306
  • SIMMONS, T. J., FRANDSEN, K. E. H., CIANO, L., TRYFONA, T., LENFANT, N., POULSEN, J. C., WILSON, L. F. L., TANDRUP, T., TOVBORG, M., SCHNORR, K., JOHANSEN, K. S., HENRISSAT, B., WALTON, P. H., LO LEGGIO, L. and DUPREE, P., 2017. NATURE COMMUNICATIONS. 8,
  • FRANDSEN, KRISTIAN E. H., SIMMONS, THOMAS J., DUPREE, PAUL, POULSEN, JENS-CHRISTIAN N., HEMSWORTH, GLYN R., CIANO, LUISA, JOHNSTON, ESTHER M., TOVBORG, MORTEN, JOHANSEN, KATJA S., VON FREIESLEBEN, PERNILLE, MARMUSE, LAURENCE, FORT, SEBASTIEN, COTTAZ, SYLVAIN, DRIGUEZ, HUGUES, HENRISSAT, BERNARD, LENFANT, NICOLAS, TUNA, FLORIANA, BALDANSUREN, AMGALANBAATAR, DAVIES, GIDEON J., LO LEGGIO, LEILA and WALTON, PAUL H., 2016. NATURE CHEMICAL BIOLOGY. 12(4), 298-+
  • CIANO, LUISA, FEY, NATALIE, HALLIDAY, CONNOR J. V., LYNAM, JASON M., MILNER, LUCY M., MISTRY, NIMESH, PRIDMORE, NATALIE E., TOWNSEND, NELL S. and WHITWOOD, ADRIAN C., 2015. CHEMICAL COMMUNICATIONS. 51(47), 9702-9705
  • YIN, DELU (TYLER), URRESTI, SAIOA, LAFOND, MICKAEL, JOHNSTON, ESTHER M., DERIKVAND, FATEMEH, CIANO, LUISA, BERRIN, JEAN-GUY, HENRISSAT, BERNARD, WALTON, PAUL H., DAVIES, GIDEON J. and BRUMER, HARRY, 2015. NATURE COMMUNICATIONS. 6,

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